Novel Triazine JPC-2067-B Inhibits Toxoplasma gondii In Vitro and In Vivo

BACKGROUND AND METHODOLOGY: Toxoplasma gondii causes substantial morbidity, mortality, and costs for healthcare in the developed and developing world. Current medicines are not well tolerated and cause hypersensitivity reactions. The dihydrotriazine JPC-2067-B (4, 6-diamino-1, 2-dihydro-2, 2-dimethy...

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Hauptverfasser: Mui, Ernest J., Schiehser, Guy A., Milhous, Wilbur K., Hsu, Honghue, Roberts, Craig W., Kirisits, Michael, Muench, Stephen, Rice, David, Dubey, J. P., Fowble, Joseph W., Rathod, Pradipsinh K., Queener, Sherry F., Liu, Susan R., Jacobus, David P., McLeod, Rima
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254147/
https://ncbi.nlm.nih.gov/pubmed/18320016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000190
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