Novel Triazine JPC-2067-B Inhibits Toxoplasma gondii In Vitro and In Vivo

BACKGROUND AND METHODOLOGY: Toxoplasma gondii causes substantial morbidity, mortality, and costs for healthcare in the developed and developing world. Current medicines are not well tolerated and cause hypersensitivity reactions. The dihydrotriazine JPC-2067-B (4, 6-diamino-1, 2-dihydro-2, 2-dimethy...

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Autors principals: Mui, Ernest J., Schiehser, Guy A., Milhous, Wilbur K., Hsu, Honghue, Roberts, Craig W., Kirisits, Michael, Muench, Stephen, Rice, David, Dubey, J. P., Fowble, Joseph W., Rathod, Pradipsinh K., Queener, Sherry F., Liu, Susan R., Jacobus, David P., McLeod, Rima
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254147/
https://ncbi.nlm.nih.gov/pubmed/18320016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000190
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