Novel Triazine JPC-2067-B Inhibits Toxoplasma gondii In Vitro and In Vivo

BACKGROUND AND METHODOLOGY: Toxoplasma gondii causes substantial morbidity, mortality, and costs for healthcare in the developed and developing world. Current medicines are not well tolerated and cause hypersensitivity reactions. The dihydrotriazine JPC-2067-B (4, 6-diamino-1, 2-dihydro-2, 2-dimethy...

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Detalhes bibliográficos
Main Authors: Mui, Ernest J., Schiehser, Guy A., Milhous, Wilbur K., Hsu, Honghue, Roberts, Craig W., Kirisits, Michael, Muench, Stephen, Rice, David, Dubey, J. P., Fowble, Joseph W., Rathod, Pradipsinh K., Queener, Sherry F., Liu, Susan R., Jacobus, David P., McLeod, Rima
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254147/
https://ncbi.nlm.nih.gov/pubmed/18320016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000190
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