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Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: distinct effect of progesterone receptor isoforms
There is strong evidence that catechol-O-methyl transferase (COMT) protects breast cells against estrogen-induced cancer by detoxifying catecholestrogens, the carcinogenic estrogen metabolites. COMT gene expression is controlled by two promoters—a proximal promoter (COMTP1) and a distal promoter (CO...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254140/ https://ncbi.nlm.nih.gov/pubmed/17689241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2007.03.049 |
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