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Progesterone receptor isoform-specific promoter methylation — Association of PRA promoter methylation with worse outcome in breast cancer patients

PURPOSE: ERα and PR levels are critical determinants for breast cancer prognosis and response to endocrine therapy. Although PR is known to be silenced by methylation of its promoter, few studies have correlated methylation with PR levels and outcome in breast cancer. There is only one previous smal...

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Detalhes bibliográficos
Main Authors: Pathiraja, Thushangi N, Shetty, Priya B, Jelinek, Jaroslav, He, Rong, Hartmaier, Ryan, Margossian, Astrid L, Hilsenbeck, Susan G, Issa, Jean-Pierre J, Oesterreich, Steffi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955277/
https://ncbi.nlm.nih.gov/pubmed/21459801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2950
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