Towards non-surgical therapy for uterine fibroids: catechol-O-methyl transferase inhibitor shrinks uterine fibroid lesions in the Eker rat model

BACKGROUND: Uterine leiomyomas (fibroids) are the most common pelvic tumors in women. We assessed the potential therapeutic utility of Ro 41-0960, a synthetic catechol-O-methyl transferase inhibitor (COMTI), in the Eker rat. METHODS: We randomized uterine fibroid-bearing Eker rats for treatment with...

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Main Authors: Hassan, M.H., Fouad, H., Bahashwan, S., Al-Hendy, A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196875/
https://ncbi.nlm.nih.gov/pubmed/21896544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/der280
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