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Regulation of Catechol-O-Methyltransferase Expression in Human Myometrial Cells

OBJECTIVE: The catechol-O-methyltransferase enzyme catalyzes the methylation of the catechol estrogens, 2- or 4-hydroxyestrogen, to 2- or 4-methoxyestrogen. Both the hydroxy estrogens and methoxy estrogens were shown to modulate the effects of estrogen. Because catechol-O-methyltransferase activity...

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Detalhes bibliográficos
Publicado no:Obstet Gynecol
Main Authors: Wentz, Melissa J., Jamaluddin, Mohammad, Garfield, Robert E., Al-Hendy, Ayman
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221853/
https://ncbi.nlm.nih.gov/pubmed/17138778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.AOG.0000243775.73788.11
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