A Single-Nucleotide Polymorphism in the Fetal Catechol-O-methyltransferase Gene is Associated With Spontaneous Preterm Birth in African Americans

Catechol-O-methyltransferase (COMT) activity has been reported to be higher in African Americans (AA) than Caucasians (Cau). COMT converts 2- and 4-hydroxy (OH) estrogens to 2- and 4-methoxyestrogens, respectively, and can increase estrogenic milieu locally in tissues. To assess whether the increase...

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Detalhes bibliográficos
Main Authors: Thota, Chandrasekhar, Menon, Ramkumar, Wentz, Melissa J., Fortunato, Stephen J., Bartlett, Jackie, Drobek, Cayce O., Nair, Sangeeta, Al-Hendy, Ayman
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343133/
https://ncbi.nlm.nih.gov/pubmed/22158829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719111417885
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