Ligand-independent pathway that controls stability of interferon alpha receptor

Ligand-specific negative regulation of cytokine-induced signaling relies on down regulation of the cytokine receptors. Down regulation of the IFNAR1 sub-unit of the Type I interferon (IFN) receptor proceeds via lysosomal receptor proteolysis, which is triggered by ubiquitination that depends on IFNA...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Liu, Jianghuai, Plotnikov, Alexander, Banerjee, Anamika, Kumar, K.G. Suresh, Ragimbeau, Josiane, Marijanovic, Zrinka, Baker, Darren P., Pellegrini, Sandra, Fuchs, Serge Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253662/
https://ncbi.nlm.nih.gov/pubmed/18166147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.12.137
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