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High yield bacterial expression of active c-Abl and c-Src tyrosine kinases

The Abl and Src tyrosine kinases are key signaling proteins that are of considerable interest as drug targets in cancer and many other diseases. The regulatory mechanisms that control the activity of these proteins are complex, and involve large-scale conformational changes in response to phosphoryl...

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Dettagli Bibliografici
Autori principali: Seeliger, Markus A., Young, Matthew, Henderson, M. Nidanie, Pellicena, Patricia, King, David S., Falick, Arnold M., Kuriyan, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253236/
https://ncbi.nlm.nih.gov/pubmed/16260764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051750905
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