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High yield bacterial expression of active c-Abl and c-Src tyrosine kinases
The Abl and Src tyrosine kinases are key signaling proteins that are of considerable interest as drug targets in cancer and many other diseases. The regulatory mechanisms that control the activity of these proteins are complex, and involve large-scale conformational changes in response to phosphoryl...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253236/ https://ncbi.nlm.nih.gov/pubmed/16260764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051750905 |
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