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High yield bacterial expression of active c-Abl and c-Src tyrosine kinases

The Abl and Src tyrosine kinases are key signaling proteins that are of considerable interest as drug targets in cancer and many other diseases. The regulatory mechanisms that control the activity of these proteins are complex, and involve large-scale conformational changes in response to phosphoryl...

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Bibliografske podrobnosti
Main Authors: Seeliger, Markus A., Young, Matthew, Henderson, M. Nidanie, Pellicena, Patricia, King, David S., Falick, Arnold M., Kuriyan, John
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253236/
https://ncbi.nlm.nih.gov/pubmed/16260764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051750905
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