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The crystal structure of a bacterial Class II ketol-acid reductoisomerase: Domain conservation and evolution

Ketol-acid reductoisomerase (KARI; EC 1.1.1.86) catalyzes two steps in the biosynthesis of branched-chain amino acids. Amino acid sequence comparisons across species reveal that there are two types of this enzyme: a short form (Class I) found in fungi and most bacteria, and a long form (Class II) ty...

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Detalhes bibliográficos
Main Authors: Tyagi, Rajiv, Duquerroy, Stephane, Navaza, Jorge, Guddat, Luke W., Duggleby, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253233/
https://ncbi.nlm.nih.gov/pubmed/16322583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051791305
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