p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein

BACKGROUND: Human papillomavirus (HPV) DNA replication can be inhibited by the cellular tumour suppressor protein p53. However, the mechanism through which p53 inhibits viral replication and the role that this might play in the HPV life cycle are not known. The papillomavirus E2 protein is required...

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Détails bibliographiques
Auteurs principaux: Brown, Craig, Kowalczyk, Anna M, Taylor, Ewan R, Morgan, Iain M, Gaston, Kevin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249571/
https://ncbi.nlm.nih.gov/pubmed/18190682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-5
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