Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA

Replication of the human papillomavirus (HPV) DNA genome relies on viral factors E1 and E2 and the cellular replication machinery. Bromodomain-containing protein 4 (Brd4) interacts with viral E2 protein to mediate papillomavirus (PV) genome maintenance and viral transcription. However, the functiona...

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Detalhes bibliográficos
Main Authors: Wang, Xin, Helfer, Christine M., Pancholi, Neha, Bradner, James E., You, Jianxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624215/
https://ncbi.nlm.nih.gov/pubmed/23365439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03068-12
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