Evidence Supporting a Role for TopBP1 and Brd4 in the Initiation but Not Continuation of Human Papillomavirus 16 E1/E2-Mediated DNA Replication

To replicate the double-stranded human papillomavirus 16 (HPV16) DNA genome, viral proteins E1 and E2 associate with the viral origin of replication, and E2 can also regulate transcription from adjacent promoters. E2 interacts with host proteins in order to regulate both transcription and replicatio...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Gauson, Elaine J., Donaldson, Mary M., Dornan, Edward S., Wang, Xu, Bristol, Molly, Bodily, Jason M., Morgan, Iain M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403487/
https://ncbi.nlm.nih.gov/pubmed/25694599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00335-15
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