SAMHD1 Regulates Human Papillomavirus 16-Induced Cell Proliferation and Viral Replication during Differentiation of Keratinocytes

Human papillomaviruses induce a host of anogenital cancers, as well as oropharyngeal cancer (HPV+OPC); human papillomavirus 16 (HPV16) is causative in around 90% of HPV+OPC cases. Using telomerase reverse transcriptase (TERT) immortalized foreskin keratinocytes (N/Tert-1), we have identified signifi...

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Udgivet i:mSphere
Main Authors: James, Claire D., Prabhakar, Apurva T., Otoa, Raymonde, Evans, Michael R., Wang, Xu, Bristol, Molly L., Zhang, Kun, Li, Renfeng, Morgan, Iain M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686230/
https://ncbi.nlm.nih.gov/pubmed/31391281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00448-19
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