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p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein

BACKGROUND: Human papillomavirus (HPV) DNA replication can be inhibited by the cellular tumour suppressor protein p53. However, the mechanism through which p53 inhibits viral replication and the role that this might play in the HPV life cycle are not known. The papillomavirus E2 protein is required...

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Detalhes bibliográficos
Main Authors: Brown, Craig, Kowalczyk, Anna M, Taylor, Ewan R, Morgan, Iain M, Gaston, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249571/
https://ncbi.nlm.nih.gov/pubmed/18190682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-5
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