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p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein

BACKGROUND: Human papillomavirus (HPV) DNA replication can be inhibited by the cellular tumour suppressor protein p53. However, the mechanism through which p53 inhibits viral replication and the role that this might play in the HPV life cycle are not known. The papillomavirus E2 protein is required...

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Autors principals: Brown, Craig, Kowalczyk, Anna M, Taylor, Ewan R, Morgan, Iain M, Gaston, Kevin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249571/
https://ncbi.nlm.nih.gov/pubmed/18190682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-5
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