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Human PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group I

The peroxisome biogenesis disorders (PBDs), including Zellweger syndrome (ZS) and neonatal adrenoleukodystrophy (NALD), are autosomal recessive diseases caused by defects in peroxisome assembly, for which at least 10 complementation groups have been reported. We have isolated a human PEX1 cDNA (HsPE...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tamura, Shigehiko, Okumoto, Kanji, Toyama, Ryusuke, Shimozawa, Nobuyuki, Tsukamoto, Toshiro, Suzuki, Yasuyuki, Osumi, Takashi, Kondo, Naomi, Fujiki, Yukio
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4350
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