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SPECIFIC PROTEIN DOMAINS MEDIATE COOPERATIVE ASSEMBLY OF HuR OLIGOMERS ON AU-RICH mRNA-DESTABILIZING SEQUENCES
The RNA-binding factor HuR is a ubiquitously expressed member of the Hu protein family that binds and stabilizes mRNAs containing AU-rich elements (AREs). Hu proteins share a common domain organization of two tandemly arrayed RNA Recognition Motifs (RRMs) near the N-terminus followed by a basic hing...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2244793/ https://ncbi.nlm.nih.gov/pubmed/17517897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701751200 |
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