SPECIFIC PROTEIN DOMAINS MEDIATE COOPERATIVE ASSEMBLY OF HuR OLIGOMERS ON AU-RICH mRNA-DESTABILIZING SEQUENCES

The RNA-binding factor HuR is a ubiquitously expressed member of the Hu protein family that binds and stabilizes mRNAs containing AU-rich elements (AREs). Hu proteins share a common domain organization of two tandemly arrayed RNA Recognition Motifs (RRMs) near the N-terminus followed by a basic hing...

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Detalhes bibliográficos
Main Authors: Fialcowitz-White, Elizabeth J., Brewer, Brandy Y., Ballin, Jeff D., Willis, Chris D., Toth, Eric A., Wilson, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244793/
https://ncbi.nlm.nih.gov/pubmed/17517897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701751200
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