Highly Selective Actions of HuR in Antagonizing AU-Rich Element-Mediated mRNA Destabilization

Human RNA-binding protein HuR, a nucleocytoplasmic shuttling protein, is a ubiquitously expressed member of the family of Hu proteins, which consist of two N-terminal RNA recognition motifs (RRM1 and RRM2), a hinge region, and a C-terminal RRM (RRM3). Although in vitro experiments showed indiscrimin...

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Detalhes bibliográficos
Main Authors: Chen, Chyi-Ying A., Xu, Nianhua, Shyu, Ann-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139819/
https://ncbi.nlm.nih.gov/pubmed/12242302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7268-7278.2002
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