A HAIRPIN-LIKE STRUCTURE WITHIN AN AU-RICH mRNA-DESTABILIZING ELEMENT REGULATES TRANS-FACTOR BINDING SELECTIVITY AND mRNA DECAY KINETICS

In mammals, rapid mRNA turnover directed by AU-rich elements (AREs) is mediated by selective association of cellular ARE-binding proteins. These trans-acting factors display overlapping RNA substrate specificities and may act to either stabilize or destabilize targeted transcripts, however, the mech...

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Hlavní autoři: Fialcowitz, Elizabeth J., Brewer, Brandy Y., Keenan, Bridget P., Wilson, Gerald M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553220/
https://ncbi.nlm.nih.gov/pubmed/15809297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M500618200
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