Crystallization and preliminary crystallographic analysis of orotidine 5′-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum

Orotidine 5′-monophosphate (OMP) decarboxylase (OMPDC; EC 4.1.1.23) catalyzes the final step in the de novo synthesis of uridine 5′-monophosphate (UMP) and defects in the enzyme are lethal in the malaria parasite Plasmodium falciparum. Active recombinant P. falciparum OMPDC (PfOMPDC) was crystallize...

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Auteurs principaux: Krungkrai, Sudaratana R., Tokuoka, Keiji, Kusakari, Yukiko, Inoue, Tsuyoshi, Adachi, Hiroaki, Matsumura, Hiroyoshi, Takano, Kazufumi, Murakami, Satoshi, Mori, Yusuke, Kai, Yasushi, Krungkrai, Jerapan, Horii, Toshihiro
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2006
Sujets:
Crystallization Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2243097/
https://ncbi.nlm.nih.gov/pubmed/16754976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106015594
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