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Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins
The inherent difficulties of stabilizing detergent-solubilized integral membrane proteins for biophysical or structural analysis demand the development of new methodologies to improve success rates. One proven strategy is the use of antibody fragments to increase the ‘soluble’ portion of any membran...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
International Union of Crystallography
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242885/ https://ncbi.nlm.nih.gov/pubmed/16946459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106029125 |
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