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Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins

The inherent difficulties of stabilizing detergent-solubilized integral membrane proteins for biophysical or structural analysis demand the development of new methodologies to improve success rates. One proven strategy is the use of antibody fragments to increase the ‘soluble’ portion of any membran...

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Détails bibliographiques
Auteurs principaux: Roosild, Tarmo P., Castronovo, Samantha, Choe, Senyon
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242885/
https://ncbi.nlm.nih.gov/pubmed/16946459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106029125
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