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Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins

The inherent difficulties of stabilizing detergent-solubilized integral membrane proteins for biophysical or structural analysis demand the development of new methodologies to improve success rates. One proven strategy is the use of antibody fragments to increase the ‘soluble’ portion of any membran...

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書目詳細資料
Main Authors: Roosild, Tarmo P., Castronovo, Samantha, Choe, Senyon
格式: Artigo
語言:Inglês
出版: International Union of Crystallography 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242885/
https://ncbi.nlm.nih.gov/pubmed/16946459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106029125
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