KTN (RCK) Domains Regulate K(+) Channels and Transporters by Controlling the Dimer-Hinge Conformation

KTN (RCK) domains are nucleotide-binding folds that form the cytoplasmic regulatory complexes of various K(+) channels and transporters. The mechanisms these proteins use to control their transmembrane pore-forming counterparts remains unclear despite numerous electrophysiological and structural stu...

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Detalhes bibliográficos
Main Authors: Roosild, Tarmo P., Castronovo, Samantha, Miller, Samantha, Li, Chan, Rasmussen, Tim, Bartlett, Wendy, Gunasekera, Banuri, Choe, Senyon, Booth, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920069/
https://ncbi.nlm.nih.gov/pubmed/19523906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.03.018
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