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Mechanism of ligand-gated potassium efflux in bacterial pathogens
Gram negative pathogens are protected against toxic electrophilic compounds by glutathione-gated potassium efflux systems (Kef) that modulate cytoplasmic pH. We have elucidated the mechanism of gating through structural and functional analysis of Escherichia coli KefC. The revealed mechanism can exp...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993342/ https://ncbi.nlm.nih.gov/pubmed/21041667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012716107 |
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