Understanding the Structural Requirements for Activators of the Kef Bacterial Potassium Efflux System

[Image: see text] The potassium efflux system, Kef, protects bacteria against the detrimental effects of electrophilic compounds via acidification of the cytoplasm. Kef is inhibited by glutathione (GSH) but activated by glutathione-S-conjugates (GS-X) formed in the presence of electrophiles. GSH and...

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Detalhes bibliográficos
Main Authors: Healy, Jessica, Ekkerman, Silvia, Pliotas, Christos, Richard, Morgiane, Bartlett, Wendy, Grayer, Samuel C., Morris, Garrett M., Miller, Samantha, Booth, Ian R., Conway, Stuart J., Rasmussen, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004266/
https://ncbi.nlm.nih.gov/pubmed/24601535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5001118
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