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Understanding the Structural Requirements for Activators of the Kef Bacterial Potassium Efflux System
[Image: see text] The potassium efflux system, Kef, protects bacteria against the detrimental effects of electrophilic compounds via acidification of the cytoplasm. Kef is inhibited by glutathione (GSH) but activated by glutathione-S-conjugates (GS-X) formed in the presence of electrophiles. GSH and...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical Society
2014
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004266/ https://ncbi.nlm.nih.gov/pubmed/24601535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5001118 |
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