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Sensitivity of secondary structure propensities to sequence differences between α- and γ-synuclein: Implications for fibrillation
The synucleins are a family of intrinsically disordered proteins involved in various human diseases. α-Synuclein has been extensively characterized due to its role in Parkinson's disease where it forms intracellular aggregates, while γ-synuclein is overexpressed in a majority of late-stage brea...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242444/ https://ncbi.nlm.nih.gov/pubmed/17088319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062465306 |
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