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New algorithms and an in silico benchmark for computational enzyme design

The creation of novel enzymes capable of catalyzing any desired chemical reaction is a grand challenge for computational protein design. Here we describe two new algorithms for enzyme design that employ hashing techniques to allow searching through large numbers of protein scaffolds for optimal cata...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zanghellini, Alexandre, Jiang, Lin, Wollacott, Andrew M., Cheng, Gong, Meiler, Jens, Althoff, Eric A., Röthlisberger, Daniela, Baker, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242439/
https://ncbi.nlm.nih.gov/pubmed/17132862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062353106
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