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Evaluation and ranking of enzyme designs

In 2008, a successful computational design procedure was reported that yielded active enzyme catalysts for the Kemp elimination. Here, we studied these proteins together with a set of previously unpublished inactive designs to determine the sources of activity or lack thereof, and to predict which o...

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Autores principales: Kiss, Gert, Röthlisberger, Daniela, Baker, David, Houk, KN
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975139/
https://ncbi.nlm.nih.gov/pubmed/20665693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.462
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