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Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination

The poly(A) (pA) signal possesses a dual function in 3′ end processing of pre-mRNA and in transcriptional termination of RNA polymerase II (Pol II) for most eukaryotic protein-coding genes. A key protein factor in yeast and Drosophila Pol II transcriptional termination is the 3′-end processing facto...

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Bibliographic Details
Main Authors: West, Steven, Proudfoot, Nicholas J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241900/
https://ncbi.nlm.nih.gov/pubmed/18086705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1112
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