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Tumor Necrosis Factor Receptor 1/c-Jun-NH(2)-Kinase Signaling Promotes Human Neoplasia
The tumor necrosis factor α receptor (TNFR1) activates downstream effectors that include the mitogen-activated protein kinase kinase 7 (MKK7)/c-Jun-NH(2)-kinase (JNK)/activator protein 1 (AP1) cascade. Here, we report that JNK is activated in a majority of spontaneous human squamous cell carcinomas...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2239246/ https://ncbi.nlm.nih.gov/pubmed/17440097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-4017 |
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