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c-Jun NH(2)-Terminal Kinase Is Essential for the Regulation of AP-1 by Tumor Necrosis Factor

The c-Jun NH(2)-terminal kinase (JNK) is activated by the cytokine tumor necrosis factor (TNF). This pathway is implicated in the regulation of AP-1-dependent gene expression by TNF. To examine the role of the JNK signaling pathway, we compared the effects of TNF on wild-type and Jnk1(−/−) Jnk2(−/−)...

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Detalhes bibliográficos
Main Authors: Ventura, Juan-Jose, Kennedy, Norman J., Lamb, Jennifer A., Flavell, Richard A., Davis, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152565/
https://ncbi.nlm.nih.gov/pubmed/12665585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.8.2871-2882.2003
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