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c-Jun Promotes whereas JunB Inhibits Epidermal Neoplasia

Deregulation of the AP1 family gene regulators have been implicated in a wide range of diseases, including cancer. Here, we report that c-Jun was activated in human squamous cell carcinoma (SCC) and coexpression of c-Jun with oncogenic Ras was sufficient to transform primary human epidermal cells in...

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Detalhes bibliográficos
Main Authors: Jin, Jane Yingai, Ke, Hengning, Hall, Russell P., Zhang, Jennifer Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108157/
https://ncbi.nlm.nih.gov/pubmed/21289643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2011.1
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