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The c-Jun N-terminal Kinase 2 Plays a Dominant Role in Human Epidermal Neoplasia

The c-Jun N-terminal Kinase (JNK) signaling cascade has been implicated in a wide range of diseases, including cancer. It is unclear how different JNK proteins contribute to human cancer. Here, we report that JNK2 is activated in over 70% of human squamous cell carcinoma (SCC) samples and that inhib...

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Detalhes bibliográficos
Main Authors: Ke, Hengning, Harris, Rebecca, Coloff, Jonathan, Jin, Jane Y., Leshin, Benjamin, de Marval, Paula Miliani, Tao, Shiying, Rathmell, Jeffrey C, Hall, Russell P., Zhang, Jennifer Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855785/
https://ncbi.nlm.nih.gov/pubmed/20354187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2923
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