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The cJUN NH(2)-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation
Breast cancer is the most commonly diagnosed malignancy in women. Analysis of breast cancer genomic DNA indicates frequent loss-of-function mutations in components of the cJUN NH(2)-terminal kinase (JNK) signaling pathway. Since JNK signaling can promote cell proliferation by activating the AP1 tran...
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| 發表在: | eLife |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5984035/ https://ncbi.nlm.nih.gov/pubmed/29856313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36389 |
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