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G12 Signaling through c-Jun NH(2)-Terminal Kinase Promotes Breast Cancer Cell Invasion
Signaling through the heterotrimeric G protein, G12, via Rho induces a striking increase in breast cancer cell invasion. In this study, evidence is provided that the c-Jun NH(2)-terminal kinase (JNK) is a key downstream effector of G12 on this pathway. Expression of constitutively-active Gα12 or act...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210117/ https://ncbi.nlm.nih.gov/pubmed/22087220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026085 |
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