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Doxazosin induces apoptosis of cells expressing hERG K(+) channels
The antihypertensive drug doxazosin has been associated with an increased risk for congestive heart failure and cardiomyocyte apoptosis. Human ether-a-go-go-related gene (hERG) K(+) channels, previously shown to be blocked by doxazosin at therapeutically relevant concentrations, represent plasma mem...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2239015/ https://ncbi.nlm.nih.gov/pubmed/18054910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2007.10.051 |
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