Regulation of two-pore-domain (K(2P)) potassium leak channels by the tyrosine kinase inhibitor genistein

BACKGROUND AND PURPOSE: Two-pore-domain potassium (K(2P)) channels mediate potassium background (or ‘leak') currents, controlling excitability by stabilizing membrane potential below firing threshold and expediting repolarization. Inhibition of K(2P) currents permits membrane potential depolari...

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Detalhes bibliográficos
Main Authors: Gierten, J, Ficker, E, Bloehs, R, Schlömer, K, Kathöfer, S, Scholz, E, Zitron, E, Kiesecker, C, Bauer, A, Becker, R, Katus, H A, Karle, C A, Thomas, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518462/
https://ncbi.nlm.nih.gov/pubmed/18516069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.213
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