Regulation of two-pore-domain (K(2P)) potassium leak channels by the tyrosine kinase inhibitor genistein

BACKGROUND AND PURPOSE: Two-pore-domain potassium (K(2P)) channels mediate potassium background (or ‘leak') currents, controlling excitability by stabilizing membrane potential below firing threshold and expediting repolarization. Inhibition of K(2P) currents permits membrane potential depolari...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gierten, J, Ficker, E, Bloehs, R, Schlömer, K, Kathöfer, S, Scholz, E, Zitron, E, Kiesecker, C, Bauer, A, Becker, R, Katus, H A, Karle, C A, Thomas, D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2008
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518462/
https://ncbi.nlm.nih.gov/pubmed/18516069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.213
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