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Cutting Edge: CD4(+) T Cell Control of CD8(+) T Cell Reactivity to a Model Tumor Antigen

Neoantigens resulting from the inherent genomic instability of tumor cells generally do not trigger immune recognition. Similarly, transfection of tumors with model Ags often fails to elicit CD8(+) T cell responses or alter a tumor's growth rate or lethality. We report here that the adoptive tr...

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Main Authors: Surman, Deborah R., Dudley, Mark E., Overwijk, Willem W., Restifo, Nicholas P.
格式: Artigo
語言:Inglês
出版: 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2239008/
https://ncbi.nlm.nih.gov/pubmed/10623795
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