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Cutting Edge: CD4(+) T Cell Control of CD8(+) T Cell Reactivity to a Model Tumor Antigen

Neoantigens resulting from the inherent genomic instability of tumor cells generally do not trigger immune recognition. Similarly, transfection of tumors with model Ags often fails to elicit CD8(+) T cell responses or alter a tumor's growth rate or lethality. We report here that the adoptive tr...

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Detalhes bibliográficos
Main Authors: Surman, Deborah R., Dudley, Mark E., Overwijk, Willem W., Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2239008/
https://ncbi.nlm.nih.gov/pubmed/10623795
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