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Role of Heme in the Antifungal Activity of the Azaoxoaporphine Alkaloid Sampangine

Sampangine, a plant-derived alkaloid found in the Annonaceae family, exhibits strong inhibitory activity against the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus. In the present study, transcriptional profiling experiments coupled with analyses...

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Detalhes bibliográficos
Main Authors: Agarwal, Ameeta K., Xu, Tao, Jacob, Melissa R., Feng, Qin, Lorenz, Michael C., Walker, Larry A., Clark, Alice M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238161/
https://ncbi.nlm.nih.gov/pubmed/18156292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00323-07
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