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Role of Heme in the Antifungal Activity of the Azaoxoaporphine Alkaloid Sampangine

Sampangine, a plant-derived alkaloid found in the Annonaceae family, exhibits strong inhibitory activity against the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus. In the present study, transcriptional profiling experiments coupled with analyses...

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Autores principales: Agarwal, Ameeta K., Xu, Tao, Jacob, Melissa R., Feng, Qin, Lorenz, Michael C., Walker, Larry A., Clark, Alice M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238161/
https://ncbi.nlm.nih.gov/pubmed/18156292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00323-07
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