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Sampangine Inhibits Heme Biosynthesis in both Yeast and Human
The azaoxoaporphine alkaloid sampangine exhibits strong antiproliferation activity in various organisms. Previous studies suggested that it somehow affects heme metabolism and stimulates production of reactive oxygen species (ROS). In this study, we show that inhibition of heme biosynthesis is the p...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209050/ https://ncbi.nlm.nih.gov/pubmed/21908598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05170-11 |
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