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Sampangine Inhibits Heme Biosynthesis in both Yeast and Human
The azaoxoaporphine alkaloid sampangine exhibits strong antiproliferation activity in various organisms. Previous studies suggested that it somehow affects heme metabolism and stimulates production of reactive oxygen species (ROS). In this study, we show that inhibition of heme biosynthesis is the p...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209050/ https://ncbi.nlm.nih.gov/pubmed/21908598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05170-11 |
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