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The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases
The etiologies of neurodegenerative diseases may be diverse; however, a common pathological denominator is the formation of aberrant protein conformers and the occurrence of pathognomonic proteinaceous deposits. Different approaches coming from neuropathology, genetics, animal modeling and biophysic...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234348/ https://ncbi.nlm.nih.gov/pubmed/18216876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601930 |
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