Cftr: Covalent and Noncovalent Modification Suggests a Role for Fixed Charges in Anion Conduction

The goal of the experiments described here was to explore the possible role of fixed charges in determining the conduction properties of CFTR. We focused on transmembrane segment 6 (TM6) which contains four basic residues (R334, K335, R347, and R352) that would be predicted, on the basis of their po...

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Hlavní autoři: Smith, Stephen S., Liu, Xuehong, Zhang, Zhi-Ren, Sun, Fang, Kriewall, Thomas E., McCarty, Nael A., Dawson, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2001
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233702/
https://ncbi.nlm.nih.gov/pubmed/11585852
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