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CFTR: Temperature-dependent cysteine reactivity suggests different stable conformers of the conduction pathway

Cysteine scanning has been widely used to identify pore-lining residues in mammalian ion channels, including the cystic fibrosis transmembrane conductance regulator (CFTR). These studies, however, have been typically conducted at room temperature rather than human body temperature. Reports of substa...

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Detalhes bibliográficos
Main Authors: Liu, Xuehong, Dawson, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229303/
https://ncbi.nlm.nih.gov/pubmed/22014307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201176q
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