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CFTR: Temperature-dependent cysteine reactivity suggests different stable conformers of the conduction pathway
Cysteine scanning has been widely used to identify pore-lining residues in mammalian ion channels, including the cystic fibrosis transmembrane conductance regulator (CFTR). These studies, however, have been typically conducted at room temperature rather than human body temperature. Reports of substa...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229303/ https://ncbi.nlm.nih.gov/pubmed/22014307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201176q |
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