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A mutation in the pore region of HERG K(+) channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation
1. The effects of a mutation in the human ether-a-go-go-related gene (HERG) (Ser631 to Ala, S631A) on the voltage- and extracellular [K(+)] dependence of inactivation were studied in Xenopus oocytes using two microelectrode and single channel voltage-clamp techniques. 2. The voltage required for hal...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2230942/ https://ncbi.nlm.nih.gov/pubmed/9547387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.129bo.x |
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