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Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes
1. The structural basis for the activation gate of voltage-dependent K(+) channels is not known, but indirect evidence has implicated the S4-S5 linker, the cytoplasmic region between the fourth and fifth transmembrane domains of the channel subunit. We have studied the effects of mutations in the S4...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269111/ https://ncbi.nlm.nih.gov/pubmed/9882738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.667ad.x |
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