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Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes

1. The structural basis for the activation gate of voltage-dependent K(+) channels is not known, but indirect evidence has implicated the S4-S5 linker, the cytoplasmic region between the fourth and fifth transmembrane domains of the channel subunit. We have studied the effects of mutations in the S4...

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Detalhes bibliográficos
Main Authors: Sanguinetti, M C, Xu, Q P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269111/
https://ncbi.nlm.nih.gov/pubmed/9882738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.667ad.x
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