Blockade of HERG channels expressed in Xenopus laevis oocytes by external divalent cations.

We have investigated actions of various divalent cations (Ba2+, Sr2+, Mn2+, Co2+, Ni2+, Zn2+) on human ether-a-go-go related gene (HERG) channels expressed in Xenopus laevis oocytes using the voltage clamp technique. All divalent cations inhibited HERG current dose-dependently in a voltage-dependent...

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Main Authors: Ho, W K, Kim, I, Lee, C O, Youm, J B, Lee, S H, Earm, Y E
格式: Artigo
語言:Inglês
出版: 1999
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300172/
https://ncbi.nlm.nih.gov/pubmed/10096894
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