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Voltage-dependent blockade of HERG channels expressed in Xenopus oocytes by external Ca(2+) and Mg(2+)
1. We expressed the human eag-related gene (HERG), which is known to encode the delayed rectifier K(+) current (I(Kr)) in cardiac muscle, in Xenopus oocytes. Using a two-microelectrode voltage clamp technique, the effect of external Ca(2+) and Mg(2+) on the HERG current (I(HERG)) was investigated. 2...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2230832/ https://ncbi.nlm.nih.gov/pubmed/9508824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.631bs.x |
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