Voltage-dependent blockade of HERG channels expressed in Xenopus oocytes by external Ca(2+) and Mg(2+)

1. We expressed the human eag-related gene (HERG), which is known to encode the delayed rectifier K(+) current (I(Kr)) in cardiac muscle, in Xenopus oocytes. Using a two-microelectrode voltage clamp technique, the effect of external Ca(2+) and Mg(2+) on the HERG current (I(HERG)) was investigated. 2...

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Main Authors: Ho, Won-Kyung, Kim, Injune, Lee, Chin O, Earm, Yung E
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1998
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230832/
https://ncbi.nlm.nih.gov/pubmed/9508824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.631bs.x
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